Genetic damage in chronic renal failure patients is associated with the glomerular filtration rate index

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Genetic damage in chronic renal failure patients is associated with the glomerular filtration rate index.

Chronic renal failure (CRF) patients are considered to present genomic instability and, as a consequence, elevated levels of genetic damage. An open question is whether this damage is related to the stage of the pathology. To determine the background levels of genetic damage, a large population of 258 Caucasian adults (201 CRF patients and 57 controls) was analysed using the micronucleus (MN) a...

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Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation.

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ژورنال

عنوان ژورنال: Mutagenesis

سال: 2010

ISSN: 0267-8357,1464-3804

DOI: 10.1093/mutage/geq047